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5 Facts you should know about

Atypical hemolytic uremic syndrome

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1

aHUS is usually caused by chronic, uncontrolled activation of the complement system

2

The disease affects both children and adults and is characterized by systemic thrombotic microangiopathy

3

Clinical signs and symptoms of complement-mediated TMA can include abdominal pain, confusion, fatigue, edema, nausea/vomiting, and diarrhea

4

Patients with aHUS often present with an abrupt onset of systemic signs and symptoms such as acute kidney failure, hypertension, myocardial infarction, stroke, or pancreatitis

5

aHUS can be inherited or acquired and does not appear to vary by race, gender, or geographic area

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